TOPMed OMICS Progress Report

Last updated : 10/12/2024

This page reports TOPMed Omics data received by the IRC.

OMICS sample numbers by study

RNA-seq

Methylation

Metabolomics

Proteomics

RNA-seq progress over time

RNA-seq QC metrics

This table shows aggregates across studies for many metrics of RNA-seq quality.    

Histogram of QC Measure

Cilck rows in the QC metrics table

Per sample RNA-seq quality metrics

Please log in using Google to download individual level QC results. Email tblackw@umich.edu if you aren't already on the whole genome sequence whitelist.

OMICS sample numbers by production center

RNA-seq Methylation Metabolomics Proteomics Total by Center
Broad - - - - -
NWGC - - - - -
NYGC - - - - -
USC - - - - -
Baylor - - - - -
Total by Type - - - -

 

Technical:
Stranded, poly-A-selected RNA, 101 bp paired end NovaSeq, target 75 M reads per sample for blood samples, 50 M reads per sample for tissue, cell sorted or globin-depleted blood samples.
Illumina EPIC methylation array, ~850 k sites.
Four metabolomics assay types: C8-pos, C-18-neg, HILIC-pos (all untargeted), plus Amide-neg with multiple reaction monitoring for ~200 target metabolites.